The San Francisco 49ers (12-4) play the Arizona Cardinals (4-12) at Levi’s Stadium. Going into this NFC West matchup, the Arizona Cardinals sit fourth in the division with four wins from 16 matches, eight games behind the first-place San Francisco 49ers. With the NFC West locked up, the San Francisco 49ers aim to continue their quest for home-field advantage in the NFC by taking a much-needed victory over the Arizona Cardinals.
49ers VS Cardinals Betting lines
49ers VS Cardinals Betting expert picks
49ers VS Cardinals Moneyline
The San Francisco 49ers are riding a nine-game winning streak heading into this Week 18 matchup. The hosts are 12-4 for the season and 7-1 at home. The Arizona Cardinals, on the other hand, are coming off a six-game losing streak, two of which took place on the road. This poor form has dropped them to 4-12.
49ers VS Cardinals Spread
The San Francisco 49ers are the 14-point favorites over the Arizona Cardinals, according to the Arizona sports betting sites. If the hosts hold that to be true, they could well be on their way to one of the biggest victories of Week 18. In the last ten matchups in this series, the average points margin between these two sides was 9.7 points.
Take the San Francisco 49ers to cover the spread as it paid off beautifully in their last four home matches, and we wouldn’t be surprised to see them cover it again on Sunday. In their previous ten games, the San Francisco 49ers went 7-3 ATS overall and 7-2 ATS in the last nine games at home.
The past 12 games against NFC West opposition saw the Arizona Cardinals end up 5-7 ATS. During that span, the offense produced 20.9 points per game and the defense allowed an average of 23.9 points. The visitors are 5-4 ATS from their nine most recent road trips, as well as 5-5 ATS in their last ten games overall.
San Francisco 49ers VS Arizona Cardinals Total
The last ten head-to-head games saw an average of 42.3 points. Based on this stat alone, the total may end somewhere between 40 and 45 points when the Arizona Cardinals visit the San Francisco 49ers.
The 40.0 total for this Week 18 matchup between the two teams is 0.2 points more than the average of 39.8-point total they put up across their past five meetings against each other.
When betting on the total in San Francisco 49ers games, consider that each of their last two matches went over. Interestedly, the total has gone under in seven of the San Francisco 49ers’ past 12 matchups against teams from the NFC West.
The score finished 3-3 against the total and averaged 43.0 points in the most recent NFC West matchups the Arizona Cardinals played away from home. Over was a winning bet three times in the past five road games for the Arizona Cardinals, who are 7-3 against the total in their last ten home and away games combined.
San Francisco 49ers VS Arizona Cardinals Betting trends
- San Francisco 49ers have covered the spread in six of their last seven games.
- San Francisco 49ers’ last three games at the Levi’s Stadium went over.
NFL Power Rankings Week 18 2022, San Francisco 49ers VS Arizona Cardinals
San Francisco 49ers Form
Form-wise, the San Francisco 49ers are looking strong on the back of nine consecutive wins. A 34-37 triumph over the Las Vegas Raiders last week extended their winning streak, leaving them 9-1 in their last 10 matches overall.
Playing at the Levi’s Stadium brings out the best in the San Francisco 49ers. They have the sixth-best home offensive record, averaging 26.8 points per game with home-field advantage and 25.8 points for all 16 of their regular season games. Visiting offenses normally struggle to break down the hosts’ defense, which has the second-best defensive record at home, having only allowed 15.0 points on their own turf and 16.5 points in all outings.
The San Francisco 49ers have clinched a playoff berth after winning their division. The NFC West champions now aim to improve their second seed in the NFC Conference going into the final week of the regular season.
Arizona Cardinals Form
The Arizona Cardinals seem to be on a bad roll against NFC West teams as they have lost seven of their last eight divisional matchups. More recently, they finished 20-19 against the Atlanta Falcons last week, leaving their past ten-game record at 2-8.
It’s been a rough few weeks for the visiting offense in terms of points scored. In the last five matches, the Arizona Cardinals have only put up 17.4 points on average which is way below their season average of 20.4 points. On the other side, the defense has struggled to contain opposing offenses, giving up 25.7 points per game this year.
The Arizona Cardinals have already been eliminated from playoff contention—a fact that’s all too obvious given that they have lost 12 of their 16 regular season games. Getting a strong pick in next year’s NFL draft is the best they can hope for now.
San Francisco 49ers VS Arizona Cardinals H2H history
The San Francisco 49ers beat the Arizona Cardinals 10-38 in their previous matchup at the Estadio Azteca on November 2022. However, this might well be one road trip the Arizona Cardinals are looking forward to, as the past ten rounds of this series make good reading for the visitors. Victory has gone their way six times, while the San Francisco 49ers came out on top four times.
The San Francisco 49ers managed an average of 21.2 points a game in their ten most recent outings against the Arizona Cardinals, who averaged 21.1 points.